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AlaRS - Alanyl-tRNA synthetase

Predicted to enable alanine-tRNA ligase activity and aminoacyl-tRNA editing activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic head epidermis; embryonic ventral epidermis; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2N; developmental and epileptic encephalopathy 29; leukodystrophy; and trichothiodystrophy. Orthologous to human AARS1 (alanyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to AlaRS

NCBI Orthologs

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Species Gene Architecture aa