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Rcd4 Reduction in Cnn dots 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34158, updated on 4-Jan-2025

Summary

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Official Symbol
Rcd4provided by FlyBase
Official Full Name
Reduction in Cnn dots 4provided by FlyBase
Primary source
FLYBASE:FBgn0032034
Locus tag
Dmel_CG17295
See related
AllianceGenome:FB:FBgn0032034
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD16838; CG17295; Dmel\CG17295; rcd4
Summary
Involved in centriole replication. Located in centriole. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Rcd4 in Genome Data Viewer
Location:
29B4-29B4; 2-31 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8382861..8383657)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8382861..8383657)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Alanyl-tRNA synthetase Neighboring gene uncharacterized protein Neighboring gene Defender against apoptotic cell death 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small nuclear RNA U6atac

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. 9-fold symmetry is not essential for centriole elongation and formation of new centriole-like structures. Panda P, et al. Nat Commun, 2024 May 25. PMID 38796459, Free PMC Article
  2. The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication. Fatalska A, et al. Elife, 2021 Mar 11. PMID 33704067, Free PMC Article
  3. Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation. Dzhindzhev NS, et al. Curr Biol, 2014 Nov 3. PMID 25264260, Free PMC Article
  4. Superresolution characterization of core centriole architecture. Tian Y, et al. J Cell Biol, 2021 Apr 5. PMID 33533934, Free PMC Article
  5. Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis. Panda P, et al. J Cell Biol, 2020 Sep 7. PMID 32543652, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis.
    Title: Tissue specific requirement of Drosophila Rcd4 for centriole duplication and ciliogenesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in centriole assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in centriole replication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in centriole IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
reduction in Cnn dots 4
Names
CG17295-PA
CG17295-PB
Rcd4-PA
Rcd4-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8382861..8383657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135377.3 → NP_609221.1  reduction in Cnn dots 4, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609221.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLM6
    Related
    FBpp0079268
    Conserved Domains (1) summary
    pfam15503
    Location:71 → 196
    PPP1R35_C; Protein phosphatase 1 regulatory subunit 35 C-terminus

  2. NM_001201793.1 → NP_001188722.1  reduction in Cnn dots 4, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188722.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VLM6
    Conserved Domains (1) summary
    pfam15503
    Location:71 → 196
    PPP1R35_C; Protein phosphatase 1 regulatory subunit 35 C-terminus
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLM6.1 Q9VLM6

Gene LinkOut

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