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CG13384 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34160, updated on 4-Jan-2025

Summary

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Official Symbol
CG13384provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032036
Locus tag
Dmel_CG13384
See related
AllianceGenome:FB:FBgn0032036
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG13384
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be active in vacuolar membrane. Is expressed in adult abdomen; adult head; and adult thorax. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG13384 in Genome Data Viewer
Location:
29B4-29C1; 2-31 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8384455..8388804)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8384455..8388804)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Reduction in Cnn dots 4 Neighboring gene Defender against apoptotic cell death 1 Neighboring gene uncharacterized protein Neighboring gene small nuclear RNA U6atac Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adipocyte amino acid sensing controls adult germline stem cell number via the amino acid response pathway and independently of Target of Rapamycin signaling in Drosophila. Armstrong AR, et al. Development, 2014 Dec. PMID 25359724, Free PMC Article
  2. Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties. Reynolds B, et al. Biochem J, 2009 May 27. PMID 19335336, Free PMC Article
  3. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Hoskins RA, et al. Genome Res, 2011 Feb. PMID 21177961, Free PMC Article
  4. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
  5. Differential amino acid transporter expression in adult Drosophila melanogaster tissues. Wright Y, et al. MicroPubl Biol, 2024. PMID 38481556, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables amino acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG13384-PB
CG13384-PC
CG13384-PD
CG13384-PE
CG13384-PF
CG13384-PG
CG13384-PH
CG13384-PI
CG13384-PJ
CG13384-PK
CG13384-PL

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8384455..8388804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164814.5 → NP_723385.1  uncharacterized protein Dmel_CG13384, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723385.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q7KTI1
    Related
    FBpp0079270
    Conserved Domains (2) summary
    COG0814
    Location:71 → 463
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:73 → 474
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  2. NM_001201794.2 → NP_001188723.1  uncharacterized protein Dmel_CG13384, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188723.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q7KTI1
    Conserved Domains (2) summary
    COG0814
    Location:71 → 463
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:73 → 474
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  3. NM_164815.5 → NP_723386.1  uncharacterized protein Dmel_CG13384, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723386.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q7KTI1
    Related
    FBpp0079272
    Conserved Domains (2) summary
    COG0814
    Location:71 → 463
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:73 → 474
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  4. NM_001201796.2 → NP_001188725.1  uncharacterized protein Dmel_CG13384, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188725.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q9VLM4
    Conserved Domains (2) summary
    COG0814
    Location:74 → 466
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:76 → 477
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  5. NM_205935.3 → NP_995657.1  uncharacterized protein Dmel_CG13384, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995657.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q7KTI1
    Conserved Domains (2) summary
    COG0814
    Location:71 → 463
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:73 → 474
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  6. NM_205936.3 → NP_995658.1  uncharacterized protein Dmel_CG13384, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995658.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q8MSR2
    Conserved Domains (2) summary
    COG0814
    Location:70 → 462
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:72 → 473
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  7. NM_164812.5 → NP_723383.1  uncharacterized protein Dmel_CG13384, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723383.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q9VLM3
    Related
    FBpp0079271
    Conserved Domains (2) summary
    COG0814
    Location:92 → 484
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:94 → 495
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  8. NM_001201795.2 → NP_001188724.1  uncharacterized protein Dmel_CG13384, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188724.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q7KTI1
    Conserved Domains (2) summary
    COG0814
    Location:71 → 463
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:73 → 474
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  9. NM_001201797.2 → NP_001188726.1  uncharacterized protein Dmel_CG13384, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188726.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q8MSR2
    Conserved Domains (2) summary
    COG0814
    Location:70 → 462
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:72 → 473
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  10. NM_164813.4 → NP_723384.1  uncharacterized protein Dmel_CG13384, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723384.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q9VLM4
    Related
    FBpp0079273
    Conserved Domains (2) summary
    COG0814
    Location:74 → 466
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:76 → 477
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  11. NM_001201798.2 → NP_001188727.1  uncharacterized protein Dmel_CG13384, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188727.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E8NH21, Q8MSR2
    Conserved Domains (2) summary
    COG0814
    Location:70 → 462
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:72 → 473
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KTI1 Q7KTI1
Q8MSR2 Q8MSR2
Q9VLM3 Q9VLM3
Q9VLM4 Q9VLM4

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