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Sgp Sgroppino [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34188, updated on 4-Jan-2025

Summary

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Official Symbol
Sgpprovided by FlyBase
Official Full Name
Sgroppinoprovided by FlyBase
Primary source
FLYBASE:FBgn0032055
Locus tag
Dmel_CG13091
See related
AllianceGenome:FB:FBgn0032055
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13091; CT32316; Dmel\CG13091; sgp
Summary
Predicted to enable alcohol-forming long-chain fatty acyl-CoA reductase activity and alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Located in peroxisomal membrane. Is expressed in adult fat body; adult head; and adult heart. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Sgp in Genome Data Viewer
Location:
29D4-29D4; 2-33 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8519690..8521809)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8519690..8521809)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class U Neighboring gene mitochondrial ribosomal protein L51 Neighboring gene Ubiquitin-like activating enzyme 4 Neighboring gene Angiotensin-converting enzyme-related Neighboring gene lemming B Neighboring gene lemming A Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. Yang H, et al. BMC Genomics, 2017 May 18. PMID 28521739, Free PMC Article
  2. The SILAC fly allows for accurate protein quantification in vivo. Sury MD, et al. Mol Cell Proteomics, 2010 Oct. PMID 20525996, Free PMC Article
  3. Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila. Merkling SH, et al. Sci Rep, 2019 Feb 14. PMID 30765784, Free PMC Article
  4. A postbiotic from Aspergillus oryzae attenuates the impact of heat stress in ectothermic and endothermic organisms. Kaufman JD, et al. Sci Rep, 2021 Mar 19. PMID 33742039, Free PMC Article
  5. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in peroxisomal membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sgroppino
Names
CG13091-PA
CG13091-PB
Sgp-PA
Sgp-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    8519690..8521809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273328.1 → NP_001260257.1  sgroppino, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260257.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0I7, Q9VLJ7
    Conserved Domains (3) summary
    cd09071
    Location:367 → 457
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:12 → 333
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:1 → 449
    PLN02996; fatty acyl-CoA reductase

  2. NM_135397.3 → NP_609241.1  sgroppino, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609241.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0I7, Q9VLJ7
    Related
    FBpp0079296
    Conserved Domains (3) summary
    cd09071
    Location:367 → 457
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:12 → 333
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:1 → 449
    PLN02996; fatty acyl-CoA reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VLJ7 Q9VLJ7

Gene LinkOut

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