Acer - Angiotensin-converting enzyme-related

Enables peptidyl-dipeptidase activity. Involved in several processes, including heart morphogenesis; positive regulation of circadian sleep/wake cycle, sleep; and regulation of heart rate. Located in extracellular space. Is expressed in several structures, including adult fat body; adult head; embryonic/larval dorsal vessel; extraembryonic structure; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); heart valve disease (multiple); and lung disease (multiple). Orthologous to human ACE (angiotensin I converting enzyme). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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