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CG4953 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34373, updated on 9-Dec-2024

Summary

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Official Symbol
CG4953provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032204
Locus tag
Dmel_CG4953
See related
AllianceGenome:FB:FBgn0032204
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4953; TRAPPC13
Summary
Predicted to be involved in Golgi vesicle transport. Located in Golgi apparatus. Part of TRAPPIII protein complex. Is expressed in adult head and organism. Orthologous to human TRAPPC13 (trafficking protein particle complex subunit 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG4953 in Genome Data Viewer
Location:
31B1-31B1; 2-40 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10266703..10268748)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10266703..10268748)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene REPTOR-binding partner Neighboring gene MOB kinase activator 3 Neighboring gene uncharacterized protein Neighboring gene Multi-substrate lipid kinase Neighboring gene trunk

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cryo-EM structure of metazoan TRAPPIII, the multi-subunit complex that activates the GTPase Rab1. Galindo A, et al. EMBO J, 2021 Jun 15. PMID 34018214, Free PMC Article
  2. The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases. Riedel F, et al. J Cell Biol, 2018 Feb 5. PMID 29273580, Free PMC Article
  3. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in Golgi vesicle transport IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of TRAPPIII protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TRAPPIII protein complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG4953-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10266703..10268748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135521.6 → NP_609365.3  uncharacterized protein Dmel_CG4953 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609365.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q95TN1, Q9VL12
    Related
    FBpp0079574
    Conserved Domains (1) summary
    pfam06159
    Location:64 → 289
    DUF974; Protein of unknown function (DUF974)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95TN1.1 Q95TN1

Gene LinkOut

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