Hand - hand
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including dendrite morphogenesis; heart development; and positive regulation of transcription elongation by RNA polymerase II. Located in nucleus. Is expressed in several structures, including cardial cell; dorsal vessel; nephrocyte; somatic precursor cell; and visceral mesoderm derivative. Orthologous to several human genes including HAND2 (heart and neural crest derivatives expressed 2). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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