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LManII - Lysosomal alpha-mannosidase II

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in mannose metabolic process. Located in extracellular region. Is expressed in several structures, including adult head; adult heart; anlage in statu nascendi; central brain anlage in statu nascendi; and clypeo-labral primordium. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Orthologous to human MAN2B1 (mannosidase alpha class 2B member 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa