Ubc2 - Ubiquitin conjugating enzyme 2
Enables ubiquitin-protein transferase activity. Involved in lipid storage. Predicted to be active in nucleus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; central brain primordium; ganglia; and head mesoderm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human UBE2E1 (ubiquitin conjugating enzyme E2 E1); UBE2E2 (ubiquitin conjugating enzyme E2 E2); and UBE2E3 (ubiquitin conjugating enzyme E2 E3). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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