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SmydA-3 SET and MYND domain containing, arthropod-specific, member 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34502, updated on 4-Jan-2025

Summary

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Official Symbol
SmydA-3provided by FlyBase
Official Full Name
SET and MYND domain containing, arthropod-specific, member 3provided by FlyBase
Primary source
FLYBASE:FBgn0262599
Locus tag
Dmel_CG43129
See related
AllianceGenome:FB:FBgn0262599
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17085; CG17086; CG43129; Dmel\CG43129
Old locus tag
Dmel_CG17085; Dmel_CG17086
Summary
Predicted to be active in nucleus. Is expressed in dorsal pharyngeal muscle cell. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See SmydA-3 in Genome Data Viewer
Location:
32B1-32B1; 2-43 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10850141..10854604)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10850141..10854604)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Porin2 Neighboring gene porin Neighboring gene DNZDHHC/NEW1 zinc finger protein 11 Neighboring gene aurora B Neighboring gene Signal transducing adaptor molecule

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
  2. Comparative genomic analysis of SET domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. Jiang F, et al. Gigascience, 2017 Jun 1. PMID 28444351, Free PMC Article
  3. Expansion of the mutually exclusive spliced exome in Drosophila. Hatje K, et al. Nat Commun, 2013. PMID 24025855
  4. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article
  5. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein-lysine N-methyltransferase activity NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SET and MYND domain containing, arthropod-specific, member 3
Names
CG43129-PC
CG43129-PD
CG43129-PE
SmydA-3-PC
SmydA-3-PD
SmydA-3-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10850141..10854604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273437.1 → NP_001260366.1  SET and MYND domain containing, arthropod-specific, member 3, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260366.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VKN9
    Conserved Domains (1) summary
    pfam00856
    Location:207 → 252
    SET; SET domain

  2. NM_001259033.2 → NP_001245962.1  SET and MYND domain containing, arthropod-specific, member 3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245962.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NCT1
    Conserved Domains (1) summary
    pfam00856
    Location:203 → 248
    SET; SET domain

  3. NM_135620.3 → NP_609464.1  SET and MYND domain containing, arthropod-specific, member 3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609464.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VKN9
    Related
    FBpp0293782
    Conserved Domains (1) summary
    pfam00856
    Location:207 → 252
    SET; SET domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NCT1 M9NCT1
Q9VKN9 Q9VKN9

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