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CG4751 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34551, updated on 4-Jan-2025

Summary

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Official Symbol
CG4751provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032348
Locus tag
Dmel_CG4751
See related
AllianceGenome:FB:FBgn0032348
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4751; Q9VKJ1
Summary
Predicted to enable metallopeptidase activity. Predicted to be active in nucleolus and nucleoplasm. Orthologous to human MPND (MPN domain containing). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG4751 in Genome Data Viewer
Location:
32D4-32D5; 2-44 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11130737..11136003)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11130737..11136003)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Csl4 Neighboring gene Nucleoporin 160kD Neighboring gene Replication factor C 38kD subunit Neighboring gene homogentisate 1,2-dioxygenase Neighboring gene Guanylyl cyclase at 32E Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways. Lee JP, et al. Mol Cancer Res, 2010 Jan. PMID 20068067, Free PMC Article
  2. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Cope GA, et al. Science, 2002 Oct 18. PMID 12183637
  3. Proapoptotic function of deubiquitinase DUSP31 in Drosophila. Sinenko SA. Oncotarget, 2017 Sep 19. PMID 29050293, Free PMC Article
  4. The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy. Pai YL, et al. Cell Death Dis, 2023 Aug 22. PMID 37607937, Free PMC Article
  5. Deubiquitylases from genes to organism. Clague MJ, et al. Physiol Rev, 2013 Jul. PMID 23899565

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal-dependent deubiquitinase activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4751-PA
NP_609495.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    11130737..11136003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135651.3 → NP_609495.1  uncharacterized protein Dmel_CG4751 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609495.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VKJ1
    Related
    FBpp0079789
    Conserved Domains (1) summary
    cd08067
    Location:278 → 463
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VKJ1.1 Q9VKJ1

Gene LinkOut

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