prd - paired

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Is expressed in several structures, including embryonic head segment; epithelium; semen-secreting cell of the male accessory gland; sense organ; and sensory nervous system primordium. Used to study prostate cancer. Human ortholog(s) of this gene implicated in Waardenburg syndrome (multiple); alveolar rhabdomyosarcoma; congenital myopathy 19; and craniofacial-deafness-hand syndrome. Orthologous to human PAX3 (paired box 3) and PAX7 (paired box 7). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

How was this calculated?