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Trm1 - tRNA methyltransferase 1

Enables tRNA (guanine(26)-N2)-dimethyltransferase activity. Involved in tRNA N2-guanine methylation. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; hindgut proper primordium; larval muscle system; and somatic muscle primordium. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 68. Orthologous to human TRMT1 (tRNA methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa