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MRP - Multidrug-Resistance like Protein 1

Enables ATPase-coupled inorganic anion transmembrane transporter activity. Involved in monoatomic anion transmembrane transport; renal tubular secretion; and response to toxic substance. Located in plasma membrane. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); bilirubin metabolic disorder (multiple); leukemia (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including ABCC1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group)). [provided by Alliance of Genome Resources, Dec 2024]

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NCBI Orthologs

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Species Gene Architecture aa