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Pk34A Protein kinase at 34A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34705, updated on 4-Jan-2025

Summary

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Official Symbol
Pk34Aprovided by FlyBase
Official Full Name
Protein kinase at 34Aprovided by FlyBase
Primary source
FLYBASE:FBgn0028410
Locus tag
Dmel_CG5182
See related
AllianceGenome:FB:FBgn0028410
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5182; Dmel\CG5182; GSK-3a; GSK3a
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Pk34A in Genome Data Viewer
Location:
34A7-34A7; 2-47 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13158810..13160173)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13158810..13160173)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44199 Neighboring gene kumgang Neighboring gene DnaJ homolog Neighboring gene Sirtuin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unusual haplotype structure at the proximal breakpoint of In(2L)t in a natural population of Drosophila melanogaster. Andolfatto P, et al. Genetics, 1999 Nov. PMID 10545460, Free PMC Article
  2. Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways. Manola MS, et al. Cells, 2021 Dec 18. PMID 34944088, Free PMC Article
  3. Integrated omics in Drosophila uncover a circadian kinome. Wang C, et al. Nat Commun, 2020 Jun 1. PMID 32483184, Free PMC Article
  4. Genetic variation in food choice behaviour of amino acid-deprived Drosophila. Toshima N, et al. J Insect Physiol, 2014 Oct. PMID 25010547
  5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein kinase at 34A
Names
CG5182-PA
Pk34A-PA
NP_609603.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13158810..13160173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135759.2 → NP_609603.1  protein kinase at 34A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609603.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3DMW1, Q9U6X0, Q9VK37
    Related
    FBpp0080013
    Conserved Domains (2) summary
    smart00220
    Location:45 → 328
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14137
    Location:39 → 334
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7KKI9 Q7KKI9
Q9VK37 Q9VK37

Gene LinkOut

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