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kuz - kuzbanian

Enables metalloendopeptidase activity. Involved in several processes, including border follicle cell migration; heart development; and nervous system development. Located in perivitelline space. Is expressed in several structures, including adult brain cell body rind; border follicle cell; embryonic/larval neuromuscular junction; epithelium; and imaginal disc. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa