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Cyp28a5 Cytochrome P450 28a5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34817, updated on 4-Jan-2025

Summary

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Official Symbol
Cyp28a5provided by FlyBase
Official Full Name
Cytochrome P450 28a5provided by FlyBase
Primary source
FLYBASE:FBgn0028940
Locus tag
Dmel_CG8864
See related
AllianceGenome:FB:FBgn0028940
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
28a5; BEST:GH10483; BG:DS00180.11; CG8864; cyp28a5; Cyp28A5; CYP28a5; CYP28A5; Dmel\CG8864; DS00180.11; gh10483
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in several structures, including adult head; embryonic small intestine; embryonic/larval midgut; embryonic/larval tracheal section; and small intestine primordium. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Cyp28a5 in Genome Data Viewer
Location:
34E5-34E5; 2-50 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13977302..13979569)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13977302..13979569)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Nimrod B5 Neighboring gene Nimrod C1 Neighboring gene Hemese Neighboring gene Nimrod C2 Neighboring gene rickets Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GeneID in Drosophila. Parra G, et al. Genome Res, 2000 Apr. PMID 10779490, Free PMC Article
  2. Gene Regulatory Variation in Drosophila melanogaster Renal Tissue. Glaser-Schmitt A, et al. Genetics, 2018 Sep. PMID 29976765, Free PMC Article
  3. The involvement of cytochrome P450 monooxygenases in methanol elimination in Drosophila melanogaster larvae. Wang SP, et al. Arch Insect Biochem Physiol, 2012 Apr. PMID 22508581
  4. Association of detoxification enzymes with butene-fipronil in larvae and adults of Drosophila melanogaster. Arain MS, et al. Environ Sci Pollut Res Int, 2018 Apr. PMID 29380196
  5. Identification and characterization of CYPs induced in the Drosophila antenna by exposure to a plant odorant. Baldwin SR, et al. Sci Rep, 2021 Oct 15. PMID 34654888, Free PMC Article

See all (51) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 28a5
Names
CG8864-PA
Cyp28a5-PA
cytochrome P450
NP_609694.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13977302..13979569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135850.3 → NP_609694.1  cytochrome P450 28a5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609694.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V419
    Related
    FBpp0080164
    Conserved Domains (1) summary
    cl12078
    Location:33 → 500
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V419.1 Q9V419

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