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CG4701 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34858, updated on 9-Dec-2024

Summary

Official Symbol
CG4701provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028868
Locus tag
Dmel_CG4701
See related
AllianceGenome:FB:FBgn0028868
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS06874.3; DmDM19DC4Z; Dmel\CG4701
Summary
Predicted to enable membrane protein dislocase activity. Predicted to be involved in extraction of mislocalized protein from mitochondrial outer membrane. Predicted to be active in mitochondrial outer membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in hyperekplexia 4. Orthologous to human ATAD1 (ATPase family AAA domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CG4701 in Genome Data Viewer
Location:
35B5-35B5; 2-50 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (14765908..14767225)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (14765908..14767225)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44858 Neighboring gene COP9 signalosome subunit 1a Neighboring gene uncharacterized protein Neighboring gene pseudo

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables membrane protein dislocase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in extraction of mislocalized protein from mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in extraction of mislocalized protein from mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in mitochondrial outer membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG4701-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    14765908..14767225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135877.3NP_609721.1  uncharacterized protein Dmel_CG4701 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609721.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MZ76, Q9V3Q1
    Related
    FBpp0080234
    Conserved Domains (3) summary
    smart00382
    Location:130265
    AAA; ATPases associated with a variety of cellular activities
    pfam00004
    Location:133265
    AAA; ATPase family associated with various cellular activities (AAA)
    cl24009
    Location:47152
    Parvo_NS1; Parvovirus non-structural protein NS1