PolD3 DNA polymerase delta subunit 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: PolD3provided by FlyBase
Official Full Name: DNA polymerase delta subunit 3provided by FlyBase
Primary source: FLYBASE:FBgn0283467
Locus tag: Dmel_CG3975
See related: AllianceGenome:FB:FBgn0283467
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:GH08865; BG:DS07295.3; CG3975; Dmel\CG3975; pol32; Pol32; rd
Summary: Enables DNA polymerase processivity factor activity. Involved in DNA metabolic process and protein-containing complex localization. Located in nucleoplasm. Part of delta DNA polymerase complex. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (15254819..15256304, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (15254819..15256304, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA polymerase processivity factor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA repair	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in DNA synthesis involved in double-strand break repair via homologous recombination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in double-strand break repair via break-induced replication	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in double-strand break repair via homologous recombination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitotic DNA replication	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein-containing complex localization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of delta DNA polymerase complex	IDA Inferred from Direct Assay more info	PubMed
located_in nucleoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
part_of zeta DNA polymerase complex	ISS Inferred from Sequence or Structural Similarity more info

Names: CG3975-PB; CG3975-PC; Pol32 polymerase delta subunit; PolD3-PB; PolD3-PC; reduced

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