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CG3793 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34928, updated on 9-Dec-2024

Summary

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Official Symbol
CG3793provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028507
Locus tag
Dmel_CG3793
See related
AllianceGenome:FB:FBgn0028507
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS09217.4; Dmel\CG3793
Summary
Predicted to enable protein C-terminal leucine carboxyl O-methyltransferase activity. Predicted to be involved in regulation of mitotic cell cycle spindle assembly checkpoint. Predicted to be active in cytosol. Is expressed in adult head and organism. Orthologous to human LCMT1 (leucine carboxyl methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG3793 in Genome Data Viewer
Location:
35D4-35D4; 2-51 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15764220..15766267)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15764220..15766267)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Mtr4 helicase Neighboring gene Gliotactin Neighboring gene weckle Neighboring gene Ku80 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide P-element screen for Drosophila synaptogenesis mutants. Liebl FL, et al. J Neurobiol, 2006 Mar. PMID 16408305, Free PMC Article
  2. A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. Laviolette MJ, et al. Genetics, 2005 Jun. PMID 15834148, Free PMC Article
  3. The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Zwarts L, et al. Nat Commun, 2015 Dec 11. PMID 26656654, Free PMC Article
  4. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
  5. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein C-terminal leucine carboxyl O-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mitotic cell cycle spindle assembly checkpoint IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3793-PA
CG3793-PB
NP_001246038.1
NP_609766.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    15764220..15766267
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259109.2 → NP_001246038.1  uncharacterized protein Dmel_CG3793, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246038.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NF32
    Conserved Domains (1) summary
    pfam04072
    Location:22 → 211
    LCM; Leucine carboxyl methyltransferase

  2. NM_135922.3 → NP_609766.1  uncharacterized protein Dmel_CG3793, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609766.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3K7
    Related
    FBpp0080320
    Conserved Domains (1) summary
    pfam04072
    Location:22 → 211
    LCM; Leucine carboxyl methyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NF32 M9NF32
Q9V3K7 Q9V3K7

Gene LinkOut

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