U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

beat-Ia beaten path Ia [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34947, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
beat-Iaprovided by FlyBase
Official Full Name
beaten path Iaprovided by FlyBase
Primary source
FLYBASE:FBgn0013433
Locus tag
Dmel_CG4846
See related
AllianceGenome:FB:FBgn0013433
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
beat; beat Ia; Beat Ia; beat-1a; Beat-Ia; beat1a; beat_1a; BG:DS00913.3; Cct; CCT; CG4846; CT15567; Dmel\CG4846; l(2)35Ea; l(2)35Eb; l(2)br47; l(2)br48; tric; TRiC
Summary
Involved in Bolwig's organ morphogenesis; axon development; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in extracellular region. Is expressed in motor neurons and presumptive embryonic/larval central nervous system. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See beat-Ia in Genome Data Viewer
Location:
35E2-35E2; 2-51 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16049965..16081684)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16049965..16081684)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44844 Neighboring gene beaten path Ic Neighboring gene uncharacterized protein Neighboring gene Bicaudal C Neighboring gene long non-coding RNA:CR44870 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Drosophila Beat protein is related to adhesion proteins that contain immunoglobulin domains. Mushegian AR. Curr Biol, 1997 Jun 1. PMID 9197251
  2. Modular structure of the Drosophila Beat protein. Bazan JF, et al. Curr Biol, 1997 Jun 1. PMID 9197253
  3. Fasciclin II and Beaten path modulate intercellular adhesion in Drosophila larval visual organ development. Holmes AL, et al. Development, 1999 Jan. PMID 9847240
  4. Motoneuron differentiation, survival and synaptogenesis. deLapeyrière O, et al. Curr Opin Genet Dev, 1997 Oct. PMID 9388781
  5. The Drosophila beaten path gene encodes a novel secreted protein that regulates defasciculation at motor axon choice points. Fambrough D, et al. Cell, 1996 Dec 13. PMID 8978609

See all (80) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Beat-Sidestep interaction network provides insights into Drosophila neuromuscular system development.
    Title: Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development.
  2. Controls adhesiveness levels in outgrowing embryonic motor axons during defasciculation. Mutants display a 'bypass' phenotype: growth cones fail to defasciculate from the pre-existing nerve and extend past their normal target muscles.
    Title: The Drosophila beaten path gene encodes a novel secreted protein that regulates defasciculation at motor axon choice points.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in Bolwig's organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in axon choice point recognition TAS
Traceable Author Statement
more info
 PubMed 
involved_in axon guidance IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in defasciculation of motor neuron axon IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in defasciculation of motor neuron axon IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in motor neuron axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in motor neuron axon guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
beaten path Ia
Names
CG4846-PA
CG4846-PB
beat-Ia-PA
beat-Ia-PB
beaten path
chaperonin containing TCP-1
triclops

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16049965..16081684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299046.1 → NP_001285975.1  beaten path Ia, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285975.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2J8L2
    Conserved Domains (1) summary
    cl11960
    Location:161 → 240
    Ig; Immunoglobulin domain

  2. NM_058160.4 → NP_477508.1  beaten path Ia, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477508.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q94534
    Related
    FBpp0080364
    Conserved Domains (1) summary
    cl11960
    Location:161 → 240
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5BIA5 Q5BIA5
Q94534 Q94534
X2J8L2 X2J8L2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools