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cni cornichon [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34967, updated on 9-Dec-2024

Summary

Official Symbol
cniprovided by FlyBase
Official Full Name
cornichonprovided by FlyBase
Primary source
FLYBASE:FBgn0000339
Locus tag
Dmel_CG5855
See related
AllianceGenome:FB:FBgn0000339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-35Fe; BG:DS02740.13; CG5855; Cni; Dmel\CG5855; IV; spnG
Summary
Predicted to enable signaling receptor binding activity. Involved in dorsal appendage formation; endoplasmic reticulum to Golgi vesicle-mediated transport; and regionalization. Located in endoplasmic reticulum membrane. Is expressed in adult head; adult heart; germarium; and nurse cell. Orthologous to several human genes including CNIH3 (cornichon family AMPA receptor auxiliary protein 3) and CNIH1 (cornichon family member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See cni in Genome Data Viewer
Location:
35F1-35F1; 2-52 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16309292..16310726, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16309292..16310726, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene crossover suppressor on 2 of Manheim Neighboring gene uncharacterized protein Neighboring gene Syntaxin 5 Neighboring gene fizzy Neighboring gene cactus Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein L4

Genomic regions, transcripts, and products

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cornichon
Names
CG5855-PA
CG5855-PB
CG5855-PC
cni-PA
cni-PB
cni-PC
spindle-G

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16309292..16310726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273566.1NP_001260495.1  cornichon, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260495.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0S2, P49858, Q53XF2, Q9V423
    UniProtKB/TrEMBL
    M9PDJ6
    Conserved Domains (1) summary
    pfam03311
    Location:7135
    Cornichon; Cornichon protein
  2. NM_165151.2NP_723959.1  cornichon, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723959.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0S2, P49858, Q53XF2, Q9V423
    UniProtKB/TrEMBL
    M9PDJ6
    Related
    FBpp0080405
    Conserved Domains (1) summary
    pfam03311
    Location:7135
    Cornichon; Cornichon protein
  3. NM_057720.3NP_477068.1  cornichon, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477068.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0S2, P49858, Q53XF2, Q9V423
    UniProtKB/TrEMBL
    M9PDJ6
    Related
    FBpp0080406
    Conserved Domains (1) summary
    pfam03311
    Location:7135
    Cornichon; Cornichon protein