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CG4278 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34970, updated on 9-Dec-2024

Summary

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Official Symbol
CG4278provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0014092
Locus tag
Dmel_CG4278
See related
AllianceGenome:FB:FBgn0014092
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-35F/36A; BG:DS02740.16; Dmel\CG4278; un5
Summary
Predicted to be active in mitochondrion. Is expressed in adult heart and organism. Orthologous to human NIF3L1 (NGG1 interacting factor 3 like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4278 in Genome Data Viewer
Location:
35F1-35F1; 2-52 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16327069..16328131)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16327069..16328131)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene cornichon Neighboring gene fizzy Neighboring gene cactus Neighboring gene mitochondrial ribosomal protein L4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Geisler R, et al. Cell, 1992 Nov 13. PMID 1423618
  2. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Şentürk M, et al. Nat Cell Biol, 2019 Mar. PMID 30804504, Free PMC Article
  3. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
  4. Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. Hall BS, et al. Aging (Albany NY), 2019 Dec 3. PMID 31794428, Free PMC Article
  5. Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease. Islam MS, et al. Hum Mol Genet, 2016 Dec 15. PMID 27794539, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4278-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16327069..16328131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135946.3 → NP_609790.1  uncharacterized protein Dmel_CG4278 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609790.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9NK57, Q9VJL4
    Related
    FBpp0080392
    Conserved Domains (1) summary
    pfam01784
    Location:16 → 251
    NIF3; NIF3 (NGG1p interacting factor 3)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9NK57.3 Q9NK57

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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