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mtgo miles to go [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34987, updated on 9-Dec-2024

Summary

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Official Symbol
mtgoprovided by FlyBase
Official Full Name
miles to goprovided by FlyBase
Primary source
FLYBASE:FBgn0259735
Locus tag
Dmel_CG42389
See related
AllianceGenome:FB:FBgn0259735
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Liang-1.16; CG13260; CG13261; CG31738; CG42389; CG4668; clone 1.16; CT15043; CT15049; Dmel\CG42389
Old locus tag
Dmel_CG13260; Dmel_CG31738
Summary
Located in plasma membrane. Is expressed in adult brain; adult head; adult mushroom body; and spermatozoon. Orthologous to several human genes including FNDC3B (fibronectin type III domain containing 3B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See mtgo in Genome Data Viewer
Location:
36A4-36A9; 2-52 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16545016..16663218)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16545016..16663218)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45355 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44151 Neighboring gene Transient receptor potential cation channel gamma Neighboring gene mir-2497 stem loop Neighboring gene hermaphrodite

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila. Syed A, et al. Dev Biol, 2019 Jan 1. PMID 30539716, Free PMC Article
  2. Genetic Variation and Potential for Resistance Development to the tTA Overexpression Lethal System in Insects. Knudsen KE, et al. G3 (Bethesda), 2020 Apr 9. PMID 32019873, Free PMC Article
  3. Centromeric binding and activity of Protein Phosphatase 4. Lipinszki Z, et al. Nat Commun, 2015 Jan 6. PMID 25562660, Free PMC Article
  4. A genome-wide scan for genes under balancing selection in Drosophila melanogaster. Croze M, et al. BMC Evol Biol, 2017 Jan 13. PMID 28086750, Free PMC Article
  5. Integrative genomic analysis reveals novel regulatory mechanisms of eyeless during Drosophila eye development. Yeung K, et al. Nucleic Acids Res, 2018 Dec 14. PMID 30295802, Free PMC Article

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
miles to go
Names
CG42389-PE
CG42389-PF
CG42389-PG
CG42389-PH
mtgo-PE
mtgo-PF
mtgo-PG
mtgo-PH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16545016..16663218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144357.2 → NP_001137829.1  miles to go, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137829.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7YZW3
    Conserved Domains (1) summary
    cd00063
    Location:1415 → 1520
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. NM_001273575.1 → NP_001260504.1  miles to go, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260504.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PD19
    Conserved Domains (1) summary
    cd00063
    Location:1130 → 1235
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  3. NM_135957.5 → NP_609801.3  miles to go, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609801.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJJ9
    Conserved Domains (1) summary
    cd00063
    Location:1113 → 1218
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  4. NM_165168.3 → NP_723981.1  miles to go, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723981.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E3CTU0, Q9VJJ8
    Conserved Domains (1) summary
    cd00063
    Location:764 → 869
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7YZW3 B7YZW3
M9PD19 M9PD19
Q9VJJ8 Q9VJJ8
Q9VJJ9 Q9VJJ9

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