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CG15141 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35044, updated on 4-Jan-2025

Summary

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Official Symbol
CG15141provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032635
Locus tag
Dmel_CG15141
See related
AllianceGenome:FB:FBgn0032635
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD24839; Dmel\CG15141; UBR7
Summary
Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Is expressed in several structures, including central brain primordium; embryonic brain; embryonic central brain neurons; somatic precursor cell; and ventral nerve cord. Orthologous to human UBR7 (ubiquitin protein ligase E3 component n-recognin 7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG15141 in Genome Data Viewer
Location:
36C7-36C7; 2-53 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (17410641..17413499)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (17410641..17413499)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Cytoplasmic linker protein 190 Neighboring gene RNA polymerase II subunit J Neighboring gene Radial spoke head protein 9 Neighboring gene Dorsal-related immunity factor Neighboring gene long non-coding RNA:CR44409 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Inactivation of effector caspases through nondegradative polyubiquitylation. Ditzel M, et al. Mol Cell, 2008 Nov 21. PMID 19026784, Free PMC Article
  2. The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2016 Aug. PMID 27552662, Free PMC Article
  3. Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. Herr DR, et al. FEBS Lett, 2004 Aug 13. PMID 15304339
  4. The PHD finger, a nuclear protein-interaction domain. Bienz M. Trends Biochem Sci, 2006 Jan. PMID 16297627
  5. Expression profiling of glial genes during Drosophila embryogenesis. Altenhein B, et al. Dev Biol, 2006 Aug 15. PMID 16762338

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15141-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    17410641..17413499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135993.4 → NP_609837.1  uncharacterized protein Dmel_CG15141 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609837.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJE3
    Related
    FBpp0080532
    Conserved Domains (2) summary
    cd15542
    Location:145 → 199
    PHD_UBR7; PHD finger found in putative E3 ubiquitin-protein ligase UBR7
    pfam02207
    Location:62 → 122
    zf-UBR; Putative zinc finger in N-recognin (UBR box)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VJE3 Q9VJE3

Gene LinkOut

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