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kel - kelch

Enables actin binding activity. Involved in actin cytoskeleton organization; cellularization; and oogenesis. Located in female germline ring canal. Is expressed in several structures, including anlage in statu nascendi; central brain anlage in statu nascendi; dorsal ectoderm anlage; gonad; and ring canal. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Orthologous to human KLHL2 (kelch like family member 2) and KLHL3 (kelch like family member 3). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa