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CG10283 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35102, updated on 4-Jan-2025

Summary

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Official Symbol
CG10283provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032681
Locus tag
Dmel_CG10283
See related
AllianceGenome:FB:FBgn0032681
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10283
Summary
Predicted to enable ubiquitin protein ligase binding activity. Predicted to be located in cytoplasm. Is expressed in dorsal ectoderm anlage; organism; trunk mesoderm anlage; and ventral ectoderm anlage. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 44 and mantle cell lymphoma. Orthologous to human CCDC50 (coiled-coil domain containing 50). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG10283 in Genome Data Viewer
Location:
36F5-36F5; 2-53 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18472964..18484513, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18472964..18484513, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene let-7 Complex Neighboring gene let-7 Neighboring gene mir-125 stem loop Neighboring gene grindelwald Neighboring gene kon-tiki Neighboring gene UDP-glycosyltransferase family 301 member D1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Sokol NS, et al. Genes Dev, 2008 Jun 15. PMID 18559475, Free PMC Article
  2. The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila. Schnorrer F, et al. Dev Cell, 2007 May. PMID 17488626
  3. The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F. Bugga L, et al. Mol Cell Biol, 2009 Jun. PMID 19332563, Free PMC Article
  4. The cis-regulatory code of Hox function in Drosophila. Sorge S, et al. EMBO J, 2012 Aug 1. PMID 22781127, Free PMC Article
  5. Integrative genomic analysis reveals novel regulatory mechanisms of eyeless during Drosophila eye development. Yeung K, et al. Nucleic Acids Res, 2018 Dec 14. PMID 30295802, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin protein ligase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10283-PA
CG10283-PB
CG10283-PC
CG10283-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18472964..18484513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169536.3 → NP_001163007.1  uncharacterized protein Dmel_CG10283, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163007.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK9, M9WDW9
    Conserved Domains (2) summary
    cl02600
    Location:440 → 497
    HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
    cl23720
    Location:14 → 132
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  2. NM_001169535.3 → NP_001163006.1  uncharacterized protein Dmel_CG10283, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163006.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JHK9, M9WDW9
    Conserved Domains (2) summary
    cl02600
    Location:440 → 497
    HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
    cl23720
    Location:14 → 132
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  3. NM_165255.4 → NP_724113.1  uncharacterized protein Dmel_CG10283, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724113.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9WDW9, Q9VJ84
    Related
    FBpp0080636
    Conserved Domains (2) summary
    cl02600
    Location:440 → 491
    HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
    cl23720
    Location:14 → 132
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

  4. NM_136035.7 → NP_609879.1  uncharacterized protein Dmel_CG10283, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609879.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9WDW9, Q9VJ84
    Related
    FBpp0080635
    Conserved Domains (2) summary
    cl02600
    Location:440 → 491
    HTH_MerR-SF; Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily
    cl23720
    Location:14 → 132
    RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JHK9 E1JHK9
Q5BHX9 Q5BHX9
Q95RA6 Q95RA6
Q9VJ84 Q9VJ84

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