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CG10621 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35152, updated on 4-Jan-2025

Summary

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Official Symbol
CG10621provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032726
Locus tag
Dmel_CG10621
See related
AllianceGenome:FB:FBgn0032726
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.13; BEST:LD26123; Dmel\CG10621
Summary
Predicted to enable S-adenosylmethionine-homocysteine S-methyltransferase activity. Predicted to be involved in S-methylmethionine cycle and methionine biosynthetic process. Is expressed in several structures, including adult fat body; amnioserosa; embryonic/larval crystal cell; procrystal cell; and yolk nucleus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG10621 in Genome Data Viewer
Location:
37B7-37B7; 2-54 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18952206..18954431, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18952206..18954431, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nedd8 ubiquitin like modifier Neighboring gene long non-coding RNA:CR44741 Neighboring gene Betaine-homocysteine S-methyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae. Vinci CR, et al. J Biol Chem, 2007 Mar 23. PMID 17264075
  2. Conservation of the behavioral and transcriptional response to social experience among Drosophilids. Shultzaberger RK, et al. Genes Brain Behav, 2019 Jan. PMID 29797548, Free PMC Article
  3. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Heinrichsen ET, et al. Mol Metab, 2014 Feb. PMID 24567903, Free PMC Article
  4. RNA-Sequencing of Drosophila melanogaster Head Tissue on High-Sugar and High-Fat Diets. Hemphill W, et al. G3 (Bethesda), 2018 Jan 4. PMID 29141990, Free PMC Article
  5. The Drosophila fragile X-related gene regulates axoneme differentiation during spermatogenesis. Zhang YQ, et al. Dev Biol, 2004 Jun 15. PMID 15183715

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables S-adenosylmethionine-homocysteine S-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in S-methylmethionine cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in methionine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10621-PA
CG10621-PB
CG10621-PC
selenocysteine methyltransferase
NP_001286071.1
NP_001286072.1
NP_609920.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18952206..18954431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136076.4 → NP_609920.1  uncharacterized protein Dmel_CG10621, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609920.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQN1, Q9VJ32
    Related
    FBpp0080732
    Conserved Domains (1) summary
    PRK09485
    Location:5 → 323
    mmuM; homocysteine methyltransferase; Provisional

  2. NM_001299143.1 → NP_001286072.1  uncharacterized protein Dmel_CG10621, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286072.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQN1, Q9VJ32
    Conserved Domains (1) summary
    PRK09485
    Location:5 → 323
    mmuM; homocysteine methyltransferase; Provisional

  3. NM_001299142.1 → NP_001286071.1  uncharacterized protein Dmel_CG10621, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286071.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQN1, Q9VJ32
    Conserved Domains (1) summary
    PRK09485
    Location:5 → 323
    mmuM; homocysteine methyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MQN1 Q8MQN1
Q9VJ32 Q9VJ32

Gene LinkOut

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