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CG10237 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35222, updated on 9-Dec-2024

Summary

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Official Symbol
CG10237provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032783
Locus tag
Dmel_CG10237
See related
AllianceGenome:FB:FBgn0032783
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10237
Summary
Predicted to enable phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Is expressed in adult head and organism. Orthologous to human TTPAL (alpha tocopherol transfer protein like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10237 in Genome Data Viewer
Location:
37E1-37E1; 2-54 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19435850..19442727, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19435850..19442727, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene RtcB RNA ligase Neighboring gene Rab9 Neighboring gene Ran GTPase activating protein Neighboring gene Heparan sulfate 2-O-sulfotransferase Neighboring gene Topoisomerase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Large-scale selective sweep among Segregation Distorter chromosomes in African populations of Drosophila melanogaster. Presgraves DC, et al. PLoS Genet, 2009 May. PMID 19412335, Free PMC Article
  2. A direct role for cohesin in gene regulation and ecdysone response in Drosophila salivary glands. Pauli A, et al. Curr Biol, 2010 Oct 26. PMID 20933422, Free PMC Article
  3. Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. Francis D, et al. G3 (Bethesda), 2021 Sep 27. PMID 34568906, Free PMC Article
  4. Microarray analysis and organization of circadian gene expression in Drosophila. McDonald MJ, et al. Cell, 2001 Nov 30. PMID 11733057
  5. Proteomic Analysis of the Ubiquitin Landscape in the Drosophila Embryonic Nervous System and the Adult Photoreceptor Cells. Ramirez J, et al. PLoS One, 2015. PMID 26460970, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in intermembrane lipid transfer ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in late endosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10237-PA
CG10237-PB
CG10237-PC
CG10237-PD
CG10237-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19435850..19442727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259162.2 → NP_001246091.1  uncharacterized protein Dmel_CG10237, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246091.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6TP94, Q9I7M3
    Conserved Domains (2) summary
    smart01100
    Location:45 → 92
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    cd00170
    Location:114 → 267
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

  2. NM_165299.2 → NP_724193.1  uncharacterized protein Dmel_CG10237, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724193.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6TP94, Q9I7M3
    Related
    FBpp0080748
    Conserved Domains (2) summary
    smart01100
    Location:45 → 92
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    cd00170
    Location:114 → 267
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

  3. NM_136123.3 → NP_609967.1  uncharacterized protein Dmel_CG10237, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609967.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6TP94, Q95RD3, Q9VIW5
    Related
    FBpp0080749
    Conserved Domains (2) summary
    smart01100
    Location:68 → 115
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    cd00170
    Location:137 → 290
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

  4. NM_165298.2 → NP_724192.1  uncharacterized protein Dmel_CG10237, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724192.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6TP94, Q8INW5
    Related
    FBpp0080750
    Conserved Domains (2) summary
    smart01100
    Location:50 → 97
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    cd00170
    Location:119 → 272
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

  5. NM_001273648.1 → NP_001260577.1  uncharacterized protein Dmel_CG10237, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260577.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C6TP94, Q8INW5
    Conserved Domains (2) summary
    smart01100
    Location:50 → 97
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    cd00170
    Location:119 → 272
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8INW5 Q8INW5
Q9I7M3 Q9I7M3
Q9VIW5 Q9VIW5

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