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CG10466 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35268, updated on 9-Dec-2024

Summary

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Official Symbol
CG10466provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032822
Locus tag
Dmel_CG10466
See related
AllianceGenome:FB:FBgn0032822
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.255; cg10466; Dmel\CG10466
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to human RBMX2 (RNA binding motif protein X-linked 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10466 in Genome Data Viewer
Location:
38A3-38A3; 2-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19792104..19792782)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19792104..19792782)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene brain-specific homeobox Neighboring gene Cd GTPase activating protein-related Neighboring gene female sterile (2) ltoPP43 Neighboring gene small nuclear RNA U5 at 38AB a Neighboring gene small nuclear RNA U4 at 38AB Neighboring gene sickie

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Border cell polarity and collective migration require the spliceosome component Cactin. Miao G, et al. J Cell Biol, 2022 Jul 4. PMID 35612426, Free PMC Article
  2. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
  3. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article
  4. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
  5. Transcription factor networks in Drosophila melanogaster. Rhee DY, et al. Cell Rep, 2014 Sep 25. PMID 25242320, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome HDA PubMed 
part_of precatalytic spliceosome HDA PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10466-PA
CG10466-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19792104..19792782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273672.2 → NP_001260601.1  uncharacterized protein Dmel_CG10466, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260601.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIS0
    Conserved Domains (2) summary
    COG0724
    Location:36 → 126
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12411
    Location:25 → 113
    RRM_ist3_like; RNA recognition motif in ist3 family

  2. NM_136159.4 → NP_610003.1  uncharacterized protein Dmel_CG10466, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610003.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIS0
    Related
    FBpp0080829
    Conserved Domains (2) summary
    COG0724
    Location:36 → 126
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12411
    Location:25 → 113
    RRM_ist3_like; RNA recognition motif in ist3 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VIS0 Q9VIS0

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