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CG14401 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35358, updated on 4-Jan-2025

Summary

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Official Symbol
CG14401provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032900
Locus tag
Dmel_CG14401
See related
AllianceGenome:FB:FBgn0032900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14401
Summary
Predicted to be involved in positive regulation of voltage-gated potassium channel activity; regulation of cholinergic synaptic transmission; and sleep. Predicted to be active in plasma membrane. Is expressed in adult heart. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG14401 in Genome Data Viewer
Location:
38F3-38F3; 2-54 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20869854..20871565)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20869854..20871565)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44981 Neighboring gene uncharacterized protein Neighboring gene skywalker Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multispecies Analysis of Expression Pattern Diversification in the Recently Expanded Insect Ly6 Gene Family. Tanaka K, et al. Mol Biol Evol, 2015 Jul. PMID 25743545, Free PMC Article
  2. The Ly6 neurotoxin-like molecule target of wit regulates spontaneous neurotransmitter release at the developing neuromuscular junction in Drosophila. Kim NC, et al. Dev Neurobiol, 2012 Dec. PMID 22467519
  3. Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. Nilton A, et al. Development, 2010 Jul. PMID 20570942, Free PMC Article
  4. boudin is required for septate junction organisation in Drosophila and codes for a diffusible protein of the Ly6 superfamily. Hijazi A, et al. Development, 2009 Jul. PMID 19502482
  5. Adaptation to Chronic Nutritional Stress Leads to Reduced Dependence on Microbiota in Drosophila melanogaster. Erkosar B, et al. mBio, 2017 Oct 24. PMID 29066546, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in positive regulation of voltage-gated potassium channel activity IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of synaptic transmission, cholinergic IEA
Inferred from Electronic Annotation
more info
  
involved_in sleep IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14401-PA
CG14401-PB
CG14401-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    20869854..20871565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136228.3 → NP_610072.2  uncharacterized protein Dmel_CG14401, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610072.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    D5A7S1, Q9VIH8
    Related
    FBpp0080959

  2. NM_001259186.2 → NP_001246115.1  uncharacterized protein Dmel_CG14401, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246115.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9NDC5

  3. NM_001273718.1 → NP_001260647.1  uncharacterized protein Dmel_CG14401, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260647.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D5A7S1, M9PGD2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9NDC5 M9NDC5
M9PGD2 M9PGD2
Q9VIH8 Q9VIH8

Gene LinkOut

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