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Nthl1 - Nth-like DNA glycosylase 1

Predicted to enable class I DNA-(apurinic or apyrimidinic site) endonuclease activity and oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity. Predicted to be involved in base-excision repair, AP site formation and nucleotide-excision repair. Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in familial adenomatous polyposis 3. Orthologous to human NTHL1 (nth like DNA glycosylase 1). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa