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Itgbn - Integrin betanu subunit

Enables protein heterodimerization activity. Involved in several processes, including melanotic encapsulation of foreign target; muscle cell cellular homeostasis; and negative regulation of synaptic assembly at neuromuscular junction. Located in membrane. Part of integrin complex. Is expressed in several structures, including gastric caecum; gut section; and midgut imaginal island. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGB4 (integrin subunit beta 4); ITGB8 (integrin subunit beta 8); and ITGBL1 (integrin subunit beta like 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa