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Tsp39D Tetraspanin 39D [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35405, updated on 9-Dec-2024

Summary

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Official Symbol
Tsp39Dprovided by FlyBase
Official Full Name
Tetraspanin 39Dprovided by FlyBase
Primary source
FLYBASE:FBgn0032943
Locus tag
Dmel_CG8666
See related
AllianceGenome:FB:FBgn0032943
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8666; Dm.Tsp39D; Dmel\CG8666
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in prostate adenocarcinoma. Orthologous to human CD9 (CD9 molecule). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Tsp39D in Genome Data Viewer
Location:
39D1-39D1; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21344607..21358271)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21344607..21358271)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR42696 Neighboring gene dimmed Neighboring gene defective transmitter release Neighboring gene Gustatory receptor 39b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional regulation of neuropeptide and peptide hormone expression by the Drosophila dimmed and cryptocephal genes. Gauthier SA, et al. J Exp Biol, 2006 May. PMID 16651547
  2. Transcriptional Feedback Links Lipid Synthesis to Synaptic Vesicle Pools in Drosophila Photoreceptors. Tsai JW, et al. Neuron, 2019 Feb 20. PMID 30737130, Free PMC Article
  3. Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma. Jeibmann A, et al. J Neurooncol, 2015 Sep. PMID 26224160
  4. Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Fradkin LG, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370414, Free PMC Article
  5. The tetraspanin superfamily in insects. Todres E, et al. Insect Mol Biol, 2000 Dec. PMID 11122467

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: 21346079-21346291 mobile_element_type = transposon:INE-1{}2236
  • Loc: 21346329-21347214 mobile_element_type = transposon:INE-1{}4114
  • Loc: 21347605-21355019 mobile_element_type = transposon:blood{}488

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tetraspanin 39D
Names
CG8666-PB
Tsp39D-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21344607..21358271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078888.4 → NP_523612.3  tetraspanin 39D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523612.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6NR56, Q9VID1
    Conserved Domains (2) summary
    cd03127
    Location:104 → 200
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:8 → 227
    Tetraspannin; Tetraspanin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VID1 Q9VID1

Gene LinkOut

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