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CG2201 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35417, updated on 9-Dec-2024

Summary

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Official Symbol
CG2201provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032955
Locus tag
Dmel_CG2201
See related
AllianceGenome:FB:FBgn0032955
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2201
Summary
Predicted to enable choline kinase activity and ethanolamine kinase activity. Predicted to be involved in CDP-choline pathway and phosphatidylethanolamine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to several human genes including CHKB (choline kinase beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG2201 in Genome Data Viewer
Location:
39E3-39E3; 2-54 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21614232..21624080, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21614232..21624080, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene no mechanoreceptor potential B Neighboring gene pseudo Neighboring gene long non-coding RNA:CR43148 Neighboring gene long non-coding RNA:CR44993 Neighboring gene Decondensation factor 31

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Han YG, et al. Curr Biol, 2003 Sep 30. PMID 14521833
  2. Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells. Hartmann B, et al. Genome Biol, 2009. PMID 19178699, Free PMC Article
  3. Analysis of lipid droplet dynamics and functions in Drosophila melanogaster. Lee H, et al. Methods Cell Biol, 2013. PMID 24099287
  4. Anterior repression of a Drosophila stripe enhancer requires three position-specific mechanisms. Andrioli LP, et al. Development, 2002 Nov. PMID 12397102
  5. Drosophila P elements preferentially transpose to replication origins. Spradling AC, et al. Proc Natl Acad Sci U S A, 2011 Sep 20. PMID 21896744, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: c21615957-21615768 mobile_element_type = transposon:INE-1{}4735
  • Loc: c21620698-21620605 mobile_element_type = transposon:INE-1{}4736
  • Loc: c21621407-21620700 mobile_element_type = transposon:INE-1{}4737
  • Loc: c21622358-21622237 mobile_element_type = transposon:INE-1{}4738

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables choline kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables choline kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ethanolamine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ethanolamine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in CDP-choline pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidylcholine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in phosphatidylethanolamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phosphatidylethanolamine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2201-PA
CG2201-PB
CG2201-PC
CG2201-PE
CG2201-PF
CG2201-PG
NP_001033931.1
NP_001033932.2
NP_001286125.1
NP_610115.2
NP_724348.1
NP_724349.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21614232..21624080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038843.3 → NP_001033932.2  uncharacterized protein Dmel_CG2201, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033932.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMF4
    Conserved Domains (1) summary
    cd05156
    Location:159 → 549
    ChoK_euk; Euykaryotic Choline Kinase

  2. NM_001299196.1 → NP_001286125.1  uncharacterized protein Dmel_CG2201, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286125.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V9R4
    Conserved Domains (1) summary
    cd05156
    Location:123 → 513
    ChoK_euk; Euykaryotic Choline Kinase

  3. NM_165386.3 → NP_724348.1  uncharacterized protein Dmel_CG2201, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724348.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V9R4
    Related
    FBpp0085275
    Conserved Domains (1) summary
    cd05156
    Location:123 → 513
    ChoK_euk; Euykaryotic Choline Kinase

  4. NM_136271.4 → NP_610115.2  uncharacterized protein Dmel_CG2201, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610115.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMF3
    Related
    FBpp0085276
    Conserved Domains (1) summary
    cd05156
    Location:20 → 410
    ChoK_euk; Euykaryotic Choline Kinase

  5. NM_165387.3 → NP_724349.1  uncharacterized protein Dmel_CG2201, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724349.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMF4
    Related
    FBpp0085277
    Conserved Domains (1) summary
    cd05156
    Location:159 → 549
    ChoK_euk; Euykaryotic Choline Kinase

  6. NM_001038842.4 → NP_001033931.1  uncharacterized protein Dmel_CG2201, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001033931.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PDP3
    Conserved Domains (1) summary
    cl21453
    Location:159 → 239
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2PDP3 Q2PDP3
Q8IMF3 Q8IMF3
Q8IMF4 Q8IMF4
Q95RP0 Q95RP0
Q9V9R4 Q9V9R4

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