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Clamp - Chromatin-linked adaptor for MSL proteins

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin-protein adaptor activity. Involved in dosage compensation by hyperactivation of X chromosome; maternal-to-zygotic transition of gene expression; and positive regulation of transcription by RNA polymerase II. Located in chromatin and nucleus. Is active in histone locus body. Is expressed in organism. [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa