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CG8245 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35503, updated on 9-Dec-2024

Summary

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Official Symbol
CG8245provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033031
Locus tag
Dmel_CG8245
See related
AllianceGenome:FB:FBgn0033031
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8245
Summary
Is expressed in adult head; embryonic brain; larval nervous system; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Orthologous to human TMEM53 (transmembrane protein 53). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG8245 in Genome Data Viewer
Location:
41F6-41F6; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5668383..5669986)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1555888..1557491)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene CCR4-NOT transcription complex subunit 3 Neighboring gene long non-coding RNA:CR45472 Neighboring gene kune-kune Neighboring gene scarface

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. Myster SH, et al. Genetics, 2004 Feb. PMID 15020470, Free PMC Article
  2. FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements. Corradini N, et al. Chromosoma, 2003 Jul. PMID 12827380
  3. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
  4. Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. Haussmann IU, et al. Genome Biol, 2008 Apr 17. PMID 18419806, Free PMC Article
  5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein
Names
CG8245-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5668383..5669986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136334.3 → NP_610178.2  uncharacterized protein Dmel_CG8245 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610178.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6G9, Q8SXH2
    Related
    FBpp0085372
    Conserved Domains (1) summary
    pfam05705
    Location:76 → 314
    DUF829; Eukaryotic protein of unknown function (DUF829)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z6G9 A1Z6G9
Q8SXH2 Q8SXH2

Gene LinkOut

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