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CG7881 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35521, updated on 9-Dec-2024

Summary

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Official Symbol
CG7881provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033048
Locus tag
Dmel_CG7881
See related
AllianceGenome:FB:FBgn0033048
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7881
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Predicted to be active in membrane. Is expressed in adult head; embryonic midgut chamber; embryonic/larval hindgut; embryonic/larval midgut; and embryonic/larval salivary gland. Human ortholog(s) of this gene implicated in gout. Orthologous to human SLC17A1 (solute carrier family 17 member 1); SLC17A3 (solute carrier family 17 member 3); and SLC17A4 (solute carrier family 17 member 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7881 in Genome Data Viewer
Location:
42A4-42A4; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5960275..5966856, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1847780..1854361, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44126 Neighboring gene antisense RNA:CR46269 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44127 Neighboring gene Bub1-related kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Embryonic expression patterns of Drosophila ACS family genes related to the human sialin gene. Laridon B, et al. Gene Expr Patterns, 2008 Apr. PMID 18255354
  2. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
  3. Functional antagonism between histone H3K4 demethylases in vivo. Di Stefano L, et al. Genes Dev, 2011 Jan 1. PMID 21205864, Free PMC Article
  4. Age-specific variation in immune response in Drosophila melanogaster has a genetic basis. Felix TM, et al. Genetics, 2012 Jul. PMID 22554890, Free PMC Article
  5. A phylogenetic analysis between humans and D. melanogaster: A repertoire of solute carriers in humans and flies. Ceder MM, et al. Gene, 2022 Jan 30. PMID 34673204

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7881-PA
CG7881-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5960275..5966856 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299215.1 → NP_001286144.1  uncharacterized protein Dmel_CG7881, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286144.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MS84
    Conserved Domains (2) summary
    cd06174
    Location:18 → 437
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:12 → 449
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  2. NM_136346.2 → NP_610190.2  uncharacterized protein Dmel_CG7881, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610190.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MS84
    Related
    FBpp0085369
    Conserved Domains (2) summary
    cd06174
    Location:18 → 437
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:12 → 449
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MS84 Q8MS84

Gene LinkOut

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