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CG3270 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35575, updated on 9-Dec-2024

Summary

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Official Symbol
CG3270provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033093
Locus tag
Dmel_CG3270
See related
AllianceGenome:FB:FBgn0033093
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3270
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be active in cytoplasm. Is expressed in adult head. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 19. Orthologous to human FOXRED1 (FAD dependent oxidoreductase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG3270 in Genome Data Viewer
Location:
42C5-42C5; 2-55 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6693430..6695187)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2580935..2582692)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribonuclease P/MRP subunit p25 Neighboring gene antisense RNA:CR44165 Neighboring gene uncharacterized protein Neighboring gene Tyrosine decarboxylase 2 Neighboring gene MOB kinase activator 4 Neighboring gene Rab2 Neighboring gene uncharacterized protein Neighboring gene chaski Neighboring gene mir-4975 stem loop

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. Schulte J, et al. J Neurosci, 2010 Apr 14. PMID 20392941, Free PMC Article
  2. Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study. Cuesta-Astroz Y, et al. Front Genet, 2021. PMID 34394179, Free PMC Article
  3. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
  4. The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment. Qu S, et al. Mol Psychiatry, 2024 Jan. PMID 37957291, Free PMC Article
  5. Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis. Zhou J, et al. Sci Adv, 2019 Sep. PMID 31555733, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial respiratory chain complex I assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3270-PA
NP_610228.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    6693430..6695187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136384.3 → NP_610228.1  uncharacterized protein Dmel_CG3270 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610228.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6N5, A8WHM4
    Related
    FBpp0085457
    Conserved Domains (1) summary
    COG0665
    Location:54 → 432
    DadA; Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z6N5 A1Z6N5
Q95U69 Q95U69

Gene LinkOut

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