Y39A1A.22 Xenotropic and polytropic retrovirus receptor 1 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y39A1A.22
Official Full Name: Xenotropic and polytropic retrovirus receptor 1 homolog
Primary source: WormBase:WBGene00012659
Locus tag: CELE_Y39A1A.22
See related: AllianceGenome:WB:WBGene00012659
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable inositol hexakisphosphate binding activity and phosphate transmembrane transporter activity. Predicted to be involved in cellular response to phosphate starvation and phosphate ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human XPR1 (xenotropic and polytropic retrovirus receptor 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Y39A1A.22 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 3

Sequence:: Chromosome: III; NC_003281.10 (10702613..10707028, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y39A1A.22 (e-PCR)
- UniSTS:312850

W09D10.3 (e-PCR)
- UniSTS:316130

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables inositol hexakisphosphate binding	IBA Inferred from Biological aspect of Ancestor more info
enables phosphate transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in cellular response to phosphate starvation	IBA Inferred from Biological aspect of Ancestor more info
involved_in phosphate ion transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in phosphate ion transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Xenotropic and polytropic retrovirus receptor 1 homolog

NP_499359.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

10702613..10707028 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066958.4 → NP_499359.3 Xenotropic and polytropic retrovirus receptor 1 homolog [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q9XX10

Conserved Domains (2) summary

cd14477
Location:2 → 158

SPX_XPR1_like; SPX domain of the xenotropic and polytropic retrovirus receptor 1 (XPR1) and related proteins

pfam03124
Location:262 → 625

EXS; EXS family