U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dhs-6 Hydroxysteroid dehydrogenase-like protein 2 [ Caenorhabditis elegans ]

Gene ID: 3565470, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
dhs-6
Official Full Name
Hydroxysteroid dehydrogenase-like protein 2
Primary source
WormBase:WBGene00000970
Locus tag
CELE_C17G10.8
See related
AllianceGenome:WB:WBGene00000970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable oxidoreductase activity. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human HSDL2 (hydroxysteroid dehydrogenase like 2). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See dhs-6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
6
Sequence:
Chromosome: II; NC_003280.10 (5617128..5619319, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transmembrane protein Neighboring gene Eukaryotic translation initiation factor 3 subunit L Neighboring gene Nuclear protein localization protein 4 homolog 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo. Gruneberg U, et al. J Cell Biol, 2002 Sep 2. PMID 12213836, Free PMC Article
  2. Voltage-dependent anion channel (VDAC-1) is required for olfactory sensing in Caenorhabditis elegans. Uozumi T, et al. Genes Cells, 2015 Oct. PMID 26223767
  3. Sperm chromatin proteomics identifies evolutionarily conserved fertility factors. Chu DS, et al. Nature, 2006 Sep 7. PMID 16943775, Free PMC Article
  4. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
  5. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Hydroxysteroid dehydrogenase-like protein 2
NP_001021972.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    5617128..5619319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026801.7 → NP_001021972.1  Hydroxysteroid dehydrogenase-like protein 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021972.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q09979
    Conserved Domains (2) summary
    PRK08278
    Location:9 → 275
    PRK08278; SDR family oxidoreductase
    pfam02036
    Location:319 → 411
    SCP2; SCP-2 sterol transfer family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools