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CG11123 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35664, updated on 9-Dec-2024

Summary

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Official Symbol
CG11123provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033169
Locus tag
Dmel_CG11123
See related
AllianceGenome:FB:FBgn0033169
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11123
Summary
Predicted to enable RNA binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. Predicted to be active in nucleolus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; central brain primordium; embryonic/larval midgut primordium; and mesoderm. Orthologous to human NOP9 (NOP9 nucleolar protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11123 in Genome Data Viewer
Location:
43C1-43C1; 2-56 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7440706..7442885)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3328211..3330390)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene sine oculis Neighboring gene long non-coding RNA:CR44203 Neighboring gene long non-coding RNA:CR44204 Neighboring gene kappaB-Ras Neighboring gene secretory Phospholipase A2 Neighboring gene uncharacterized protein Neighboring gene Fatty acid 2-hydroxylase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of INOS, a Gene Encoding myo-Inositol Phosphate Synthase, Causes Male Sterility in Drosophila melanogaster. Jackson NAM, et al. G3 (Bethesda), 2018 Aug 30. PMID 29991509, Free PMC Article
  2. RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs. Seinen E, et al. PLoS One, 2010 Oct 1. PMID 20957038, Free PMC Article
  3. A high-throughput pipeline for the production of synthetic antibodies for analysis of ribonucleoprotein complexes. Na H, et al. RNA, 2016 Apr. PMID 26847261, Free PMC Article
  4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11123-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7440706..7442885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136432.2 → NP_610276.1  uncharacterized protein Dmel_CG11123 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610276.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JX95
    Related
    FBpp0088044
    Conserved Domains (1) summary
    smart00025
    Location:112 → 134
    Pumilio; Pumilio-like repeats
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JX95 Q7JX95

Gene LinkOut

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