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Cul4 - Cullin 4

Enables ubiquitin ligase complex scaffold activity. Involved in several processes, including chaeta morphogenesis; eggshell chorion gene amplification; and regulation of signal transduction. Located in nucleus. Part of Cul4-RING E3 ubiquitin ligase complex. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Cabezas type. Orthologous to several human genes including CUL4A (cullin 4A). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Cul4

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Species Gene Architecture aa