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LRP1 - LDL receptor protein 1

Predicted to enable low-density lipoprotein particle receptor activity. Involved in regulation of axon guidance. Located in dendrite. Is expressed in adult brain cell body rind; adult head; and spermatozoon. Used to study epilepsy. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); keratosis pilaris atrophicans; lung disease (multiple); myocardial infarction; and sciatic neuropathy. Orthologous to several human genes including LRP1B (LDL receptor related protein 1B). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa