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CG12780 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35834, updated on 9-Dec-2024

Summary

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Official Symbol
CG12780provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033301
Locus tag
Dmel_CG12780
See related
AllianceGenome:FB:FBgn0033301
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12780; GNBP-like
Summary
Predicted to enable carbohydrate binding activity. Involved in defense response to virus. Predicted to be located in cell surface. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG12780 in Genome Data Viewer
Location:
44D2-44D2; 2-59 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8551859..8552290, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4439364..4439795, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Maltase A8 Neighboring gene mangetout Neighboring gene long non-coding RNA:CR44279 Neighboring gene long non-coding RNA:CR45308 Neighboring gene Cytochrome P450 6a14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Induction of host defence responses by Drosophila C virus. Hedges LM, et al. J Gen Virol, 2008 Jun. PMID 18474566
  2. Contrasting evolutionary patterns in Drosophila immune receptors. Jiggins FM, et al. J Mol Evol, 2006 Dec. PMID 17103056, Free PMC Article
  3. Suppression of Drosophila antifungal immunity by a parasite effector via blocking GNBP3 and GNBP-like 3, the dual receptors for β-glucans. Lu M, et al. Cell Rep, 2024 Jan 23. PMID 38175756
  4. The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila. Dostert C, et al. Nat Immunol, 2005 Sep. PMID 16086017
  5. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease. Garrido-Maraver J, et al. Biol Open, 2020 Jan 14. PMID 31822473, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables carbohydrate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in defense response to virus IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in detection of biotic stimulus ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cell surface ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12780-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8551859..8552290 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136544.3 → NP_610388.1  uncharacterized protein Dmel_CG12780 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610388.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0ZWY3, A0ZWY4
    Related
    FBpp0087815
    Conserved Domains (1) summary
    pfam15886
    Location:6 → 97
    CBM39; Carbohydrate binding domain (family 32)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0ZWY4 A0ZWY4

Gene LinkOut

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