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Lnpk Lunapark [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35842, updated on 4-Jan-2025

Summary

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Official Symbol
Lnpkprovided by FlyBase
Official Full Name
Lunaparkprovided by FlyBase
Primary source
FLYBASE:FBgn0033309
Locus tag
Dmel_CG8735
See related
AllianceGenome:FB:FBgn0033309
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8735; Dmel\CG8735; DmLnp
Summary
Predicted to be involved in endoplasmic reticulum tubular network organization. Located in endomembrane system. Is expressed in adult head. Orthologous to human LNPK (lunapark, ER junction formation factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Lnpk in Genome Data Viewer
Location:
44D4-44D4; 2-59 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8596972..8599962, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4484477..4487467, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene regular Neighboring gene uncharacterized protein Neighboring gene Calcium-independent receptor for alpha-latrotoxin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum. Chen S, et al. Proc Natl Acad Sci U S A, 2015 Jan 13. PMID 25548161, Free PMC Article
  2. A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses. Dubruille R, et al. PLoS Genet, 2009 Dec. PMID 20041201, Free PMC Article
  3. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
  4. The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria. Ge DT, et al. Mol Cell, 2019 Jun 6. PMID 31076285, Free PMC Article
  5. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum tubular network organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum tubular network organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
is_active_in endoplasmic reticulum tubular network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
lunapark
Names
CG8735-PA
CG8735-PB
Lnpk-PA
Lnpk-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8596972..8599962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299272.1 → NP_001286201.1  lunapark, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286201.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2N0
    Conserved Domains (1) summary
    pfam10058
    Location:247 → 297
    zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein

  2. NM_136551.3 → NP_610395.1  lunapark, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610395.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2N0
    Related
    FBpp0087809
    Conserved Domains (1) summary
    pfam10058
    Location:247 → 297
    zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K2N0 Q7K2N0

Gene LinkOut

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