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CG8635 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35850, updated on 4-Jan-2025

Summary

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Official Symbol
CG8635provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033317
Locus tag
Dmel_CG8635
See related
AllianceGenome:FB:FBgn0033317
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8635
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytosol. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; epithelial tube; gut section; and larval muscle cell. Orthologous to human ZC3H15 (zinc finger CCCH-type containing 15). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG8635 in Genome Data Viewer
Location:
44D5-44D5; 2-59 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8630207..8631962, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4517712..4519467, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene beta-1,3-Galactosyltransferase II Neighboring gene Gle1 RNA export mediator Neighboring gene long non-coding RNA:CR44281 Neighboring gene patched Neighboring gene Acyl-CoA synthetase long-chain Neighboring gene Ubiquinol-cytochrome c reductase 11 kDa subunit-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD. Park J, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34551427, Free PMC Article
  2. Drosophila Gut Immune Pathway Suppresses Host Development-Promoting Effects of Acetic Acid Bacteria. Lee J, et al. Mol Cells, 2023 Oct 31. PMID 37853687, Free PMC Article
  3. Highly effective proximate labeling in Drosophila. Zhang B, et al. G3 (Bethesda), 2021 May 7. PMID 33724396, Free PMC Article
  4. In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor. Baker FC, et al. Development, 2021 Nov 15. PMID 35020877, Free PMC Article
  5. SUMO-Enriched Proteome for Drosophila Innate Immune Response. Handu M, et al. G3 (Bethesda), 2015 Aug 18. PMID 26290570, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8635-PA
CG8635-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8630207..8631962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136557.3 → NP_610401.1  uncharacterized protein Dmel_CG8635, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610401.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JWR9
    UniProtKB/TrEMBL
    A0A0B4LEV3
    Related
    FBpp0087806
    Conserved Domains (3) summary
    smart00356
    Location:94 → 120
    ZnF_C3H1; zinc finger
    COG5252
    Location:1 → 314
    COG5252; Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function prediction only]
    pfam16543
    Location:219 → 314
    DFRP_C; DRG Family Regulatory Proteins, Tma46

  2. NM_001299273.1 → NP_001286202.1  uncharacterized protein Dmel_CG8635, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286202.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7JWR9
    UniProtKB/TrEMBL
    A0A0B4LEV3
    Conserved Domains (3) summary
    smart00356
    Location:94 → 120
    ZnF_C3H1; zinc finger
    COG5252
    Location:1 → 314
    COG5252; Uncharacterized conserved protein, contains CCCH-type Zn-finger protein [General function prediction only]
    pfam16543
    Location:219 → 314
    DFRP_C; DRG Family Regulatory Proteins, Tma46
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LEV3 A0A0B4LEV3
Q7JWR9.1 Q7JWR9

Gene LinkOut

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