babo - baboon
Enables activin binding activity and activin receptor activity, type I. Involved in several processes, including determination of adult lifespan; imaginal disc morphogenesis; and nervous system development. Located in plasma membrane. Part of activin receptor complex. Is expressed in several structures, including adult head; embryonic/larval fat body; embryonic/larval gut; female germline cell; and imaginal disc. Human ortholog(s) of this gene implicated in several diseases, including Loeys-Dietz syndrome 1; Lynch syndrome; carcinoma (multiple); gastrointestinal system cancer (multiple); and malignant mesothelioma. Orthologous to human ACVR1B (activin A receptor type 1B); ACVR1C (activin A receptor type 1C); and TGFBR1 (transforming growth factor beta receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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