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CG1902 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35993, updated on 9-Dec-2024

Summary

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Official Symbol
CG1902provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033434
Locus tag
Dmel_CG1902
See related
AllianceGenome:FB:FBgn0033434
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1902
Summary
Predicted to enable lipid transfer activity and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in familial isolated deficiency of vitamin E. Orthologous to human TTPA (alpha tocopherol transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG1902 in Genome Data Viewer
Location:
45F6-45F6; 2-61 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9594045..9605624)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5481550..5493129)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene closca Neighboring gene uncharacterized protein Neighboring gene Microtubule-associated protein 60 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44285 Neighboring gene Glutathione S transferase T1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
  2. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article
  3. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
  4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
  5. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables lipid transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatidylinositol bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol bisphosphate binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in intermembrane lipid transfer ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in late endosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1902-PA
CG1902-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9594045..9605624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136663.4 → NP_610507.1  uncharacterized protein Dmel_CG1902, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610507.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K1M4
    Related
    FBpp0087614
    Conserved Domains (2) summary
    smart01100
    Location:28 → 69
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:100 → 248
    CRAL_TRIO; CRAL/TRIO domain

  2. NM_165689.3 → NP_724815.1  uncharacterized protein Dmel_CG1902, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724815.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K1M4
    Related
    FBpp0087615
    Conserved Domains (2) summary
    smart01100
    Location:28 → 69
    CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
    pfam00650
    Location:100 → 248
    CRAL_TRIO; CRAL/TRIO domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K1M4 Q7K1M4

Gene LinkOut

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