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CG12134 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36038, updated on 9-Dec-2024

Summary

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Official Symbol
CG12134provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033471
Locus tag
Dmel_CG12134
See related
AllianceGenome:FB:FBgn0033471
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CKIalpha like; Dmel\CG12134
Summary
Is expressed in embryonic/larval midgut; larval muscle system; and organism. Orthologous to human WDR89 (WD repeat domain 89). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG12134 in Genome Data Viewer
Location:
46C9-46C9; 2-61 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9971143..9972780)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5858648..5860285)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit j Neighboring gene antisense RNA:CR46453 Neighboring gene long non-coding RNA:CR46455 Neighboring gene antisense RNA:CR43948 Neighboring gene even skipped

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. Fujioka M, et al. PLoS Genet, 2016 Feb. PMID 26910731, Free PMC Article
  2. Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains. Van Bortle K, et al. Genome Res, 2012 Nov. PMID 22722341, Free PMC Article
  3. Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation. Hare EE, et al. PLoS Genet, 2008 Jun 27. PMID 18584029, Free PMC Article
  4. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
  5. Mechanisms of Interaction between Enhancers and Promoters in Three Drosophila Model Systems. Kyrchanova O, et al. Int J Mol Sci, 2023 Feb 2. PMID 36769179, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein
Names
CG12134-PA
CG12134-PC
CG12134-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9971143..9972780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136698.3 → NP_610542.1  uncharacterized protein Dmel_CG12134, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610542.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JRI4, Q7JZ37
    Related
    FBpp0087476
    Conserved Domains (2) summary
    sd00039
    Location:59 → 101
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:56 → 384
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_001382018.1 → NP_001368943.1  uncharacterized protein Dmel_CG12134, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z827, Q7JRI4
    Conserved Domains (2) summary
    sd00039
    Location:58 → 100
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:55 → 383
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_001382019.1 → NP_001369072.1  uncharacterized protein Dmel_CG12134, isoform D [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7JRI4, Q7JZ37
    Conserved Domains (2) summary
    sd00039
    Location:59 → 101
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:56 → 384
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z827 A1Z827
Q7JRI4 Q7JRI4
Q7JZ37 Q7JZ37

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